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1

A High-Throughput Method for Direct Detection of Therapeutic Oligonucleotide-Induced Gene Silencing In Vivo

Coles, Andrew H., Osborn, Maire F., Alterman, Julia F., Turanov, Anton A., Godinho, Bruno M.D.C., Kennington, Lori, Chase, Kathryn, Aronin, Neil, Khvorova, Anastasia

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2015

Language:

english

File:

PDF, 532 KB

english, 2015

2

Hydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse Brain

Alterman, Julia F, Hall, Lauren M, Coles, Andrew H, Hassler, Matthew R, Didiot, Marie-Cecile, Chase, Kathryn, Abraham, Jasmin, Sottosanti, Emily, Johnson, Emily, Sapp, Ellen, Osborn, Maire F, Difiglia

Journal:

Molecular Therapy — Nucleic Acids

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

3

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

Sharma, Vivek Kumar, Osborn, Maire F., Hassler, Matthew, Echeverria, Dimas, Ly, Socheata, Ulashchik, Egor, Martynenko-Makaev, Yury, Shmanai, Vadim V, Zatsepin, Timofei S., Khvorova, Anastasia, Watts,

Journal:

Bioconjugate Chemistry

Year:

2018

Language:

english

File:

PDF, 953 KB

english, 2018

4

The crystalline composition of normal equine urine deposits

T. S. MAIR, R. S. OSBORN

Journal:

Equine Veterinary Journal

Year:

1990

Language:

english

File:

PDF, 204 KB

english, 1990

5

Picazoplatin, an Azide-Containing Platinum(II) Derivative for Target Analysis by Click Chemistry

White, Jonathan D., Osborn, Maire F., Moghaddam, Alan D., Guzman, Lindsay E., Haley, Michael M., DeRose, Victoria J.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

6

RNA Crosslinking and Click Chemistry with Platinum Compounds

DeRose, Victoria J., Plakos, Kory, Golden, Barbara L., White, Jonathan, Osborn, Maire, Moghaddam, Alan

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 74 KB

english, 2014

7

Platinum-RNA Modifications Following Drug Treatment in S. cerevisiae Identified by Click Chemistry and Enzymatic Mapping

Osborn, Maire F., White, Jonathan D., Haley, Michael M., DeRose, Victoria J.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 5.09 MB

english, 2014

8

Excited State Proton Transfer in the Red Fluorescent Protein mKeima

Henderson, J. Nathan, Osborn, Maire F., Koon, Nayden, Gepshtein, Rinat, Huppert, Dan, Remington, S. James

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 434 KB

english, 2009

9

RNA-Pt Adducts Following Cisplatin Treatment of Saccharomyces cerevisiae

Hostetter, Alethia A., Osborn, Maire F., DeRose, Victoria J.

Journal:

ACS Chemical Biology

Year:

2012

Language:

english

File:

PDF, 2.24 MB

english, 2012

10

Taking charge of siRNA delivery

Khvorova, Anastasia, Osborn, Maire F, Hassler, Matthew R

Journal:

Nature Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.33 MB

english, 2014

11

Corrigendum: Taking charge of siRNA delivery

Khvorova, Anastasia, Osborn, Maire F, Hassler, Matthew R

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 96 KB

english, 2015

12

Guanabenz (Wytensin™) selectively enhances uptake and efficacy of hydrophobically modified siRNAs

Osborn, Maire F., Alterman, Julia F., Nikan, Mehran, Cao, Hong, Didiot, Marie C., Hassler, Matthew R., Coles, Andrew H., Khvorova, Anastasia

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 2.91 MB

english, 2015

13

ChemInform Abstract: Picazoplatin, an Azide-Containing Platinum(II) Derivative for Target Analysis by Click Chemistry.

White, Jonathan D., Osborn, Maire F., Moghaddam, Alan D., Guzman, Lindsay E., Haley, Michael M., DeRose, Victoria J.

Journal:

Year:

2014

File:

PDF, 19 KB

2014

14

Docosahexaenoic Acid Conjugation Enhances Distribution and Safety of siRNA upon Local Administration in Mouse Brain

Nikan, Mehran, Osborn, Maire F, Coles, Andrew H, Godinho, Bruno MDC, Hall, Lauren M, Haraszti, Reka A, Hassler, Matthew R, Echeverria, Dimas, Aronin, Neil, Khvorova, Anastasia

Journal:

Molecular Therapy — Nucleic Acids

Year:

2016

Language:

english

File:

PDF, 3.12 MB

english, 2016

15

Synthesis and Evaluation of Parenchymal Retention and Efficacy of a Metabolically Stable, O -phosphocholine- N -docosahexaenoyl-L-serine siRNA Conjugate in Mouse Brain

Nikan, Mehran, Osborn, Maire F., Coles, Andrew H, Biscans, Annabelle, Godinho, Bruno, Haraszti, Reka, Sapp, Ellen, Echeverria, Dimas, DiFiglia, Marian, Aronin, Neil, Khvorova, Anastasia

Journal:

Bioconjugate Chemistry

Year:

2017

Language:

english

File:

PDF, 1.24 MB

english, 2017

16

Randomised control trial of the impact of a brief tele-support intervention on initial attendance at physiotherapy group sessions for pelvic floor problems

Osborne, Lisa A., Whittall, C. Mair, Emanuel, Ruth, Emery, Simon, Reed, Phil

Journal:

Archives of Physical Medicine and Rehabilitation

Year:

2017

Language:

english

File:

PDF, 2.95 MB

english, 2017

17

Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo

Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Dav

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 7.50 MB

english, 2018

18

Efficient gene silencing in brain tumors with hydrophobically modified siRNAs

Osborn, Maire F, Coles, Andrew H, Golebiowski, Diane, Echeverria, Dimas, Moazami, Michael P., Watts, Jonathan K., Sena-Esteves, Miguel, Khvorova, Anastasia

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 3.52 MB

english, 2018

19

Improving Small Interfering RNA Delivery In Vivo Through Lipid Conjugation

Osborn, Maire F., Khvorova, Anastasia

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2018

Language:

english

File:

PDF, 708 KB

english, 2018

20

Diverse lipid conjugates for functional extra-hepatic siRNA delivery in vivo

Biscans, Annabelle, Coles, Andrew, Haraszti, Reka, Echeverria, Dimas, Hassler, Matthew, Osborn, Maire, Khvorova, Anastasia

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 12.99 MB

english, 2018

21

Impact of strength and nature of patient health values on compliance and outcomes for physiotherapy treatment for pelvic floor dysfunction

Reed, Phil, Whittall, C. Mair, Osborne, Lisa A, Emery, Simon

Journal:

Year:

2019

Language:

english

File:

PDF, 622 KB

english, 2019

22

Impact of strength and nature of patient health values on compliance and outcomes for physiotherapy treatment for pelvic floor dysfunction

Reed, Phil, Whittall, C. Mair, Osborne, Lisa A, Emery, Simon

Journal:

Year:

2019

File:

PDF, 622 KB

2019

23

Crystalline composition of equine urinary calculi

MAIR, T.S., OSBORN, R.S.

Journal:

Research in Veterinary Science

Year:

1986

Language:

english

File:

PDF, 444 KB

english, 1986